By Gert Lubec
A new promising animal version of DS is suggested and this opens new possibilities to review pathomechanisms and pharmacological techniques because it is greater than tough to hold out reports in people and the scientific positive factors are hugely variable. when it comes to biology, phone cycle and stem phone experiences and by way of biochemistry, relevance of reports on a particular protein kinase, channels, transporters, superoxide dismutase, antioxidant process, chromosome meeting issue and different vital organic buildings are supplied. And back, the gene dosage speculation is addressed and even supposing nearly all of chromosome 21 gene items is unchanged in fetal DS mind, a couple of particular chromosome 21 encoded constructions together with transcription elements are certainly overexpressed even supposing findings in fetal DS are varied from these in grownup DS mind while Alzheimer-like neuropathology supervenes.
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Advances in Down Syndrome Research (Journal of Neural Transmission. Supplementa) by Gert Lubec